L13 ANS Organisation

Innervation

• Origin: Spinal Cord
• 2 Neurones: Preganglionic & Post

Pre-ganglionic: Secretes ACh into synapse

Tonic Activation

→ Post-Ganglionic. Stimulated. Secretes Noradrenaline/ACh onto target.

Innervates Involuntary tissues: Cardiac muscle, Smooth muscle, Glands

GVA, GVE

Homeostasis

Reciprocal - One decreases as the other increases

• Sympathetic - Fight, Flight, Fright
• Para-Sympathetic - Rest, Digest, Energy Storage

Neuromodulation

• Presynaptic:
• Postsynaptic:

Ganglia

• Sympathetic
• Para-Sympathetic

ANS Actions