L20 CNS Injury - Damage & Repair

CNS Damage

• Spinal Cord Injury
• Traumatic Brain Injury
• Stroke
• Brain Cancer

Old, Young(15-24)

M>F

• Sport, RTA Common Causes
• Functional Consequences: Depend on: SITE, SIZE
• CNS Energy Use

Injury

• Skull Fracture: Crack, Compound, Depressed
• Cerebral Haemorrhage: Vascular damage → Blood leakage → (Clots)
• Cerebral Amyloid Angiopathy: Fibrous Protein Deposit in Vascular network
• Arterio-Venous Malformation
• Aneurysms
• Lacunar Infarcts: White matter tissue death, Fluid filled hole remains. Presents with Syncope first → Multi Infarct Dementia. Untreated Hypertension/Diabetics
• Traumatic Brain Injury
• Consequences:
  • Response(4)
  • Long Term Consequence