Intro

pdf L01 Intro

L02 Membrane Physiology

pdf L02 Membrane Physiology

Cell membrane creates an internal environment that is different from that outside the cell.

Intracellular compartment//extracellular

Untitled

Hydrophobic central layer

Selectively concentrating various charged species within the intracellular comp

eg: organelles, proteins, cations/anions

→ Creates a concentration gradient→ electrochemical gradient→ electrical potential

Resting Membrane Potential

Nerve cell

Interior negative, exterior positive (-65 to -70mV) wrt outside

Resting membrane potential varies between cell type

Electrically Excitable cells are able to 'discharge' the standing potential = Action Potential

eg. Nerve Cells, Muscle Cells(cardiac)