Congenital Collagen malformation
Collagen is designed to support and connect structures within the body, if improperly formed, it will be weak and impaired in its function.
Dermis embryonically derived from Somatic Mesoderm
AD/AR depending on type.
Major:
Generalised Joint Hypermobility(dislocation, subluxation), Skin Hyperextensibility(soft, doughy, velvety), Atrophic Scarring, Easy Bruising(blood vessel fragility), Club foot
Vascular: BP control, Surgery avoidance, Care during pregnancy
Others: Pain medication.
Potential for Gene therapies in future.
'Split Spine'