Skin Histology

.pdf S05 Structure and function of the skin, .pdf S05 Montage Skin Images, .pdf Histology of Skin slides

Skin - Integumentary

• Functions
• 3 Layers
• Skin Appendages
• Disorders

L08 Storage and Retrieval of Genetic Information

.ppt Genetic Information

Structures of Nucleic Acids

• DNA - Double stranded, Phosphodiester backbone, Nitrogenous bases, Stable
• RNA - Single stranded (can form double stranded sections), Phosphodiester backbone, Nitrogenous bases, Uracil used for Thymine, Ribose C2 has OH → Unstable.
• Base pairs: Base pairs are the information stored.
• Room for 1 purine/pyramidine within the helix. Allows for tight double helix
• Strand sequence on one side, dictates the other.

Genomes

• Protein coding genes <5% of our genome.
• Gene regulatory elements, promotion, may be far from gene; upstream/downstream from sequence.
• Genes split by regions of non-coding DNA, RNA sections must then be spliced out (Introns).
• Repeat sequences. Eg LINE & SINE. 1.4-6Kb. Approx 20% of DNA, source thought to be Viral, used for DNA fingerprinting.