Parathyroid Part 2

Mineral Homeostasis

• 99% Bone - Skeleton: Protection, musculoskeletal support, reservoir
• 1% Soluble(serum) - neurological, cell adhesion
• Serum Calcium: 2.1-2.6mM/l - 50% bound (Albumin)
• Ca Movement: Serum ↔ Kidney, Intestine, Bone
• PTH
• Calcitonin
• FGF23

Mineral Disorders & Bone Disease

Vitamin D Deficiency

Vitamin D: Fat soluble steroid, Hormonal activity.

Use: Bone development, Ca Homeostasis. In conjunction with PTH, maintains bone health

• Functions:

• Synthesis:

• Risk factors:

• Presentation: Asymptomatic until prolonged

• Diagnosis:

• Treatment: